george-pickens.jpg
USATSI

There were six teams favored by at least one touchdown in Week 11, but the Week 12 NFL spreads only list one larger than four points on Sunday. Kansas City is a nine-point favorite at Las Vegas, while every other game is expected to be a nailbiter. One of the premier games on the Week 12 NFL schedule features the Eagles (-3.5) vs. Bills, as Buffalo tries to avoid falling back to the .500 mark overall this season. Which side of that game should you target with your Week 12 NFL parlay picks and NFL bets?

Minnesota is hoping to bounce back from a last-minute loss to Denver when it hosts Chicago on Monday Night Football in another primetime game. The Vikings are playing under journeyman quarterback Joshua Dobbs and are 3.5-point favorites in the Week 12 NFL odds. Before you make any Week 12 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine's proven computer model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2023 NFL season on an incredible 175-126 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 29-18 roll on top-rated NFL picks since Week 7 of last season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 12. If you successfully parlay its picks, you'd be looking at a massive payout of around 25-1. You can only see the model's Week 12 NFL picks at SportsLine.

Top Week 12 NFL picks

After simulating every game 10,000 times, the model is high on the Pittsburgh Steelers (-1) to cover on the road against the Cincinnati Bengals. Cincinnati is 10-2 in its last 12 home games, but will not have star quarterback Joe Burrow for the remainder of the season. The Bengals have not been able to move the ball consistently this season and it will be difficult for them to correct those issues without their starting quarterback.

This is not an ideal first matchup for backup quarterback Jake Browning, who is tasked with facing a Steelers defense that ranks seventh in the NFL in scoring. Pittsburgh has covered the spread in 10 of its last 14 games and it is 16-4 in its last 20 trips to Cincinnati. SportsLine's model is expecting another successful trip to Paycor Stadium for the Steelers, who are covering the spread in almost 60% of simulations. See which other NFL parlay picks to make here.

How to make Week 12 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including two underdogs that win outright. You can only see the model's NFL Week 12 best bets and parlay at SportsLine

What are the model's top Week 12 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 12 NFL best bets from a model on a 175-126 run on top-rated picks, and find out.