The Mississippi State Bulldogs will try to win their sixth game of the season and become bowl-eligible when they host the Ole Miss Rebels in the 2023 Egg Bowl on Thanksgiving night at Davis Wade Stadium in Starkville, Miss. The Bulldogs (5-6 overall, 1-6 in SEC) are one win away from officially clinching bowl eligibility. But if Mississippi State were to lose on Thursday, the team could still earn a bowl invitation if there are not enough six-win teams. Meanwhile, the Rebels (9-2, 5-2) are fighting to earn just the program's second 10-win regular season and a spot in a New Year's Day bowl game.

Kickoff is scheduled for 7:30 p.m. ET. The Rebels are 10-point favorites in the latest Ole Miss vs. Mississippi State odds via SportsLine consensus, while the over/under for total points scored is 54. Before making any Mississippi State vs. Ole Miss picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, the proprietary computer model has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now, the model has set its sights on Ole Miss vs. Mississippi State and just locked in its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are several college football odds and trends for Mississippi State vs. Ole Miss:

  • Mississippi State vs. Ole Miss spread: Rebels -10
  • Mississippi State vs. Ole Miss over/under: 54 points
  • Mississippi State vs. Ole Miss money line: Rebels -388, Bulldogs +303
  • MISS: The Rebels rank fourth in the country in fewest turnovers (seven)
  • MSST: LB Jett Johnson leads the conference in total tackles (99)
  • Mississippi State vs. Ole Miss: See picks at SportsLine  
  • Mississippi State vs. Ole Miss: live stream: fubo (try for free)

Why Ole Miss can cover

Sophomore Quinshon Judkins already is one of the best running backs in program history. The 5-foot-11 Judkins ranks second in Ole Miss history with 30 rushing touchdowns, third in all-purpose touchdowns (32) and fifth in rushing yards (2,500) despite playing just 24 career games. He is just 67 rushing yards away from becoming just the second Ole Miss player – and the first since 1950 – to break 1,000 rushing yards in a season twice.

In addition, the Ole Miss offense face a Mississippi State defense that has struggled in the red zone this season. Opponents are scoring on 91.2% of drives in the red zone against the Bulldogs, which ranks 116th in the country. That bodes well for an Ole Miss team that ranks 48th in the nation in red zone offense (86.8%). See which team to pick here.

Why Mississippi State can cover

Senior linebacker Nathaniel Watson is a relentless playmaker on defense. The 6-foot-2, 245-pound senior ranks second in the conference in tackles (116), one year after finishing second in the SEC last season. In a 41-20 victory over Southern Miss last week, Watson made a career-high 21 tackles, the most by an SEC defender since 2017. He also registered a forced fumble and his 10th sack of the season.

In addition, Watson and the rest of the Mississippi State defense face an Ole Miss offense that has struggled with penetration this season. The Rebels rank 114th in the country in tackles for loss allowed per game (7.18). They also are 80th in sacks allowed per game (2.27). See which team to pick here.

How to make Ole Miss vs. Mississippi State picks

SportsLine's model is leaning Under the point total, predicting a combined 54 points. The model also says one side of the spread hits over 60% of the time. You can see the model's CFB picks at SportsLine

So who wins Mississippi State vs. Ole Miss, and which side of the spread hits more than 60% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.