Starkville, Miss., will be the center of the college football world on Thanksgiving with the No. 12 Ole Miss Rebels and the Mississippi State Bulldogs set to square off in the 2023 Egg Bowl. The Bulldogs can become bowl-eligible with a victory and enter Thursday's matchup coming off a 41-20 win over Southern Miss. The Rebels have their sights set on a New Year's Six bowl game and a win on Thursday would make that a near certainty. Ole Miss beat Louisiana-Monroe 35-3 in its last outing. Ole Miss leads the all-time series 64–46–6, but the bitter in-state rivals have split the last 10 games.

Kickoff is scheduled for 7:30 p.m. ET at Davis Wade Stadium in Starkville. The Rebels are 10-point favorites in the latest Ole Miss vs. Mississippi State odds via SportsLine consensus, while the over/under for total points scored is 54. Before you make any Mississippi State vs. Ole Miss picks, be sure to check out the college football predictions and betting advice from SportsLine football expert Jimmie Kaylor

Kaylor is a NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has been red-hot all season, going 69-28-2 overall on his college football best bets for SportsLine this season so far. He is up over 42.05 units, returning a profit of $4,205 for $100 bettors. Anyone who has followed his picks this season is way up.

Now, he has set his sights on Ole Miss vs. Mississippi State and just locked in his picks and CFB predictions. You can head to SportsLine now to see Kaylor's picks. Here are several college football odds and betting lines for Mississippi State vs. Ole Miss:

  • Ole Miss vs. Mississippi State spread: Ole Miss -10
  • Ole Miss vs. Mississippi State over/under: 54
  • Ole Miss vs. Mississippi State money line: Ole Miss -397, Mississippi State +308
  • MISS: The Rebels are 5-4-1 against the spread in 2023.
  • MSU: The Bulldogs are 2-8 against the spread in 2023.
  • Ole Miss vs. Mississippi State picks: See picks at SportsLine
  • Ole Miss vs. Mississippi State live stream: fubo (try for free)

Why Ole Miss can cover

The Rebels enter this matchup with a 9-2 overall record with their only two losses coming against the top two teams in the SEC --Georgia and Alabama. Ole Miss can likely lock up a spot in a New Year's Six bowl game with a win, and the Rebels will surely be out for revenge after losing last year's Egg Bowl 24-22. Moreover, keeping their in-state rival from reaching bowl eligibility will likely serve as added motivation for the Rebels.

Ole Miss has a high-powered offense that will be hard for Mississippi State to contain if the Rebels get rolling early. Quarterback Jaxson Dart has played at a high level, completing 66.4% of his passes for 2,889 yards, 19 touchdowns, and five interceptions, while also rushing for 347 yards and seven TDs. His top target has been wide receiver Tre Harris, who enters this matchup with 44 catches for 824 yards and eight touchdowns. Running back Quinshon Judkins (933 yards, 14 TDs) could go over the 1,000-yard mark for the season in this matchup. See which team to pick at SportsLine

Why Mississippi State can cover

Mississippi State is in the process of finding its next full time head coach, but still has plenty to play for in the Egg Bowl 2023. The Bulldogs will become bowl-eligible with a win, which would extend their streak of qualifying for bowl games to 14 years. A win would also give MSU back-to-back wins in the Egg Bowl for the first time since 2011. 

Mississippi State has an above average rushing attack that showed major signs of life in its first game under interim head coach Greg Knox. In their win over Southern Miss, the Bulldogs rushed for 238 yards and averaged 5.3 yards per carry. Running back Jo'Quavious Marks leads the team with 534 rushing yards and four TDs. See which team to back at SportsLine.

How to make Mississippi State vs. Ole Miss picks

Kaylor has analyzed this matchup from every angle and he's leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

Who wins Ole Miss vs. Mississippi State on Saturday, and which critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see the picks, all from the expert who has covered college football for over a decade and is 69-28-2 on his best bets in 2023, and find out.